USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: TCPA_HUMAN USC-OGP 2-DE database:  TCPA_HUMAN TCPA_HUMAN General information about the entry View entry in simple text format Entry name TCPA_HUMAN Primary accession number P17987 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=T-complex protein 1 subunit alpha; Short=TCP-1-alpha; AltName: Full=CCT-alpha;. Gene name Name=TCP1 Synonyms=CCT1, CCTA Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0337: pI=5.60; Mw=60151 SPOT OGP-0339: pI=5.71; Mw=59965 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0650: pI=5.71; Mw=58284 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1135: pI=5.94; Mw=63519 Cross-references UniProtKB/Swiss-Prot P17987; TCPA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TCPA_HUMAN Primary accession number P17987 Secondary accession number(s) E1P5B2 Q15556 Q5TCM3 Sequence was last modified on  November 1, 1990 (version 1) Annotations were last modified on  March 15, 2017 (version 183) Name and origin of the protein Description RecName: Full=T-complex protein 1 subunit alpha; Short=TCP-1-alpha; AltName: Full=CCT-alpha; Gene name Name=TCP1 Synonyms=CCT1, CCTA Encoded on Name=TCP1; Synonyms=CCT1, CCTA Keywords Acetylation; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X52882; CAA37064.1; -; mRNA EMBL BT006969; AAP35615.1; -; mRNA EMBL AL135914; CAI21851.1; -; Genomic_DNA EMBL CH471051; EAW47616.1; -; Genomic_DNA EMBL CH471051; EAW47618.1; -; Genomic_DNA EMBL BC000665; AAH00665.1; -; mRNA EMBL M26885; AAA61059.1; -; Genomic_DNA EMBL M27272; AAA61060.1; -; Genomic_DNA EMBL M26889; AAA61060.1; JOINED; Genomic_DNA CCDS CCDS5269.1; -; . PIR S10486; S10486; . RefSeq NP_110379.2; NM_030752.2; . UniGene Hs.363137; -; . ProteinModelPortal P17987; -; . SMR P17987; -; . BioGrid 112810; 207; . DIP DIP-33676N; -; . IntAct P17987; 128; . MINT MINT-4999235; -; . STRING 9606.ENSP00000317334; -; . iPTMnet P17987; -; . PhosphoSitePlus P17987; -; . SwissPalm P17987; -; . BioMuta TCP1; -; . DMDM 135538; -; . OGP P17987; -; . REPRODUCTION-2DPAGE IPI00290566; -; . REPRODUCTION-2DPAGE P17987; -; . UCD-2DPAGE P17987; -; . EPD P17987; -; . MaxQB P17987; -; . PaxDb P17987; -; . PeptideAtlas P17987; -; . PRIDE P17987; -; . DNASU 6950; -; . Ensembl ENST00000321394; ENSP00000317334; ENSG00000120438; . GeneID 6950; -; . KEGG hsa:6950; -; . UCSC uc003qsr.4; human; . CTD 6950; -; . DisGeNET 6950; -; . GeneCards TCP1; -; . HGNC HGNC:11655; TCP1; . HPA CAB017460; -; . HPA HPA027337; -; . HPA HPA031082; -; . MIM 186980; gene; . neXtProt NX_P17987; -; . OpenTargets ENSG00000120438; -; . PharmGKB PA36406; -; . eggNOG KOG0360; Eukaryota; . eggNOG COG0459; LUCA; . GeneTree ENSGT00550000074878; -; . HOGENOM HOG000226729; -; . HOVERGEN HBG001052; -; . InParanoid P17987; -; . KO K09493; -; . OMA HYLAQEG; -; . OrthoDB EOG091G04HL; -; . PhylomeDB P17987; -; . TreeFam TF106331; -; . Reactome R-HSA-389957; Prefoldin mediated transfer of substrate to CCT/TriC; . Reactome R-HSA-389960; Formation of tubulin folding intermediates by CCT/TriC; . Reactome R-HSA-390450; Folding of actin by CCT/TriC; . Reactome R-HSA-390471; Association of TriC/CCT with target proteins during biosynthesis; . Reactome R-HSA-5620922; BBSome-mediated cargo-targeting to cilium; . Reactome R-HSA-6814122; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; . ChiTaRS TCP1; human; . GeneWiki T-complex_1; -; . GenomeRNAi 6950; -; . PRO PR:P17987; -; . Proteomes UP000005640; Chromosome 6; . Bgee ENSG00000120438; -; . CleanEx HS_TCP1; -; . ExpressionAtlas P17987; baseline and differential; . Genevisible P17987; HS; . GO GO:0001669; C:acrosomal vesicle; IEA:Ensembl; . GO GO:0044297; C:cell body; IEA:Ensembl; . GO GO:0005813; C:centrosome; IDA:MGI; . GO GO:0005832; C:chaperonin-containing T-complex; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005794; C:Golgi apparatus; IEA:Ensembl; . GO GO:0005874; C:microtubule; IDA:UniProtKB; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0005720; C:nuclear heterochromatin; IEA:Ensembl; . GO GO:0000242; C:pericentriolar material; IEA:Ensembl; . GO GO:0002199; C:zona pellucida receptor complex; IEA:Ensembl; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0044183; F:protein binding involved in protein folding; IBA:GO_Central; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0031625; F:ubiquitin protein ligase binding; IPI:ParkinsonsUK-UCL; . GO GO:0051082; F:unfolded protein binding; IBA:GO_Central; . GO GO:0006458; P:'de novo' protein folding; IBA:GO_Central; . GO GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl; . GO GO:0061077; P:chaperone-mediated protein folding; IBA:GO_Central; . GO GO:1904851; P:positive regulation of establishment of protein localization to telomere; IMP:BHF-UCL; . GO GO:1904871; P:positive regulation of protein localization to Cajal body; IMP:BHF-UCL; . GO GO:0051973; P:positive regulation of telomerase activity; IMP:BHF-UCL; . GO GO:1904874; P:positive regulation of telomerase RNA localization to Cajal body; IMP:BHF-UCL; . GO GO:0032212; P:positive regulation of telomere maintenance via telomerase; IMP:BHF-UCL; . GO GO:0006457; P:protein folding; TAS:Reactome; . GO GO:0050821; P:protein stabilization; IMP:BHF-UCL; . GO GO:2000109; P:regulation of macrophage apoptotic process; IEA:Ensembl; . GO GO:0090666; P:scaRNA localization to Cajal body; IMP:BHF-UCL; . GO GO:1901998; P:toxin transport; IEA:Ensembl; . GO GO:0044053; P:translocation of peptides or proteins into host cell cytoplasm; IEA:Ensembl; . GO GO:0007021; P:tubulin complex assembly; NAS:UniProtKB; . CDD cd03335; TCP1_alpha; 1; . Gene3D 1.10.560.10; -; 2; . Gene3D 3.30.260.10; -; 2; . Gene3D 3.50.7.10; -; 1; . InterPro IPR012715; Chap_CCT_alpha; . InterPro IPR017998; Chaperone_TCP-1; . InterPro IPR002194; Chaperonin_TCP-1_CS; . InterPro IPR002423; Cpn60/TCP-1; . InterPro IPR027409; GroEL-like_apical_dom; . InterPro IPR027413; GROEL-like_equatorial; . InterPro IPR027410; TCP-1-like_intermed; . PANTHER PTHR11353:SF145; PTHR11353:SF145; 1; . Pfam PF00118; Cpn60_TCP1; 1; . PRINTS PR00304; TCOMPLEXTCP1; . SUPFAM SSF52029; SSF52029; 1; . TIGRFAMs TIGR02340; chap_CCT_alpha; 1; . PROSITE PS00750; TCP1_1; 1; . PROSITE PS00751; TCP1_2; 1; . PROSITE PS00995; TCP1_3; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]